RNAlib-2.4.15
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Functions for incorporation of ligands binding to hairpin and interior loop motifs using the soft constraints framework. More...
Go to the source code of this file.
Data Structures | |
struct | vrna_sc_motif_s |
Typedefs | |
typedef struct vrna_sc_motif_s | vrna_sc_motif_t |
Functions | |
int | vrna_sc_add_hi_motif (vrna_fold_compound_t *vc, const char *seq, const char *structure, FLT_OR_DBL energy, unsigned int options) |
Add soft constraints for hairpin or interior loop binding motif. More... | |
Functions for incorporation of ligands binding to hairpin and interior loop motifs using the soft constraints framework.
typedef struct vrna_sc_motif_s vrna_sc_motif_t |
@addtogroup constraints_ligand @brief Ligand binding to specific hairpin/interior loop like motifs using the @ref soft_constraints feature Here is an example that adds a theophylline binding motif. Free energy contribution is derived from @f$k_d = 0.32 \mu mol / l @f$, taken from Jenison et al. 1994 @image html theo_aptamer.svg @image latex theo_aptamer.eps @code{.c}
vrna_sc_add_hi_motif(vc, "GAUACCAG&CCCUUGGCAGC", "(...((((&)...)))...)", -9.22, VRNA_OPTION_DEFAULT);